Anti-Wrinkle Injection Aftercare: Why It Matters & What Happens If You Ignore It

Anti-wrinkle injections (like Botox® or other neuromodulators) are a popular and effective way to smooth fine lines and give the face a refreshed, youthful appearance. But what many people overlook is how important aftercare is to ensure the best results — and to avoid complications.

What To Do After Anti-Wrinkle Injections

Immediately after your treatment, your practitioner will give you specific instructions. Here’s a quick overview of standard aftercare:

Stay upright for at least 4 hours post-treatment.
Avoid touching, rubbing, or massaging the treated area for 24 hours.
No makeup for at least 6 hours.
Skip the gym, saunas, hot showers, and alcohol for 24–48 hours.
Avoid lying down flat or sleeping on your face the first night.
No facial treatments, chemical peels, or microneedling for 1–2 weeks.

These rules might seem strict, but they’re there for a reason: they help the product settle properly and reduce the risk of unwanted side effects.

What Happens If You Don’t Follow Aftercare?

Ignoring aftercare advice can lead to unwanted results or complications. Here are some of the most common side effects when aftercare isn’t respected:

1. Bruising and Swelling

Touching or rubbing the treated area increases the risk of bruising. Exercising too soon also raises blood flow to the face, making bruising worse.

2. Uneven Results

Lying down or applying pressure (like sleeping on your face) can cause the product to migrate, leading to asymmetry or a “droopy” effect on the brows or eyelids (called ptosis).

3. Headaches or Discomfort

Skipping the recommended rest period may lead to headaches or a tight sensation in the forehead. It’s usually temporary but avoidable with proper care.

4. Infection

Applying makeup too soon or touching the area with unclean hands can introduce bacteria, increasing the risk of infection.

5. Shorter Duration of Results

If the product doesn’t settle correctly into the muscle, the effects may wear off faster, meaning you’ll need a top-up sooner than expected.

The Bottom Line

Anti-wrinkle injections are quick and minimally invasive, but the results are only as good as your aftercare. Taking 24–48 hours to follow simple guidelines can help you avoid side effects, ensure even, natural-looking results, and make your treatment last longer.